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Extrauma Cream

Extrauma® is the first world-wide topical r-Hirudin with dual effect as anti-thrombotic and anti-inflammatory effects. Extrauma® is produced via the patented innovative Hansenula polymorpha technology.

Ingredient: Topical r-Hirudin
Multinational Partner: Rhein Biotech
Launch Date: March 9, 2008
Pack: Tube of 25 gm

Product General

Disease Area

Trauma is a body wound or shock produced by sudden physical injury, as from violence or accident. It can also be described as a physical wound or injury, such as a fracture or blow. Major trauma, defined by an Injury Severity Score of greater than 15, can result in secondary complications such as circulatory shock, respiratory failure and death, and resuscitation of a trauma patient can often involve multiple management procedures. Trauma is the sixth leading cause of death worldwide, accounting for 10% of all mortalities, and is therefore a serious public health problem with significant social and economic costs.

Insert leaflet


Each 100 gm contains 280 I.U. of Recombinant hirudin.


Contusions, distortions, muscular tears, traumatic hematomas, edema, erythema, varicositis, periphlebitis and anal periphlebitis with hemorrhoids.


  • Dispense 2-3 cm of cream, two – three times per day and carry out a light massage until complete absorption.
  • Local rectal application for hemorrhoids using the supplied dispenser two to three times per day.

1-Documents Section

Coagulation- Inflammation Cross Talk

Thrombin in inflammation

Efficacy of Topical Hirudin

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Office Address

El-Bardissi St., 2T Takseem Asmaa Fahmy St., Heliopolis,
Cairo - Egypt.
Phone:(+202) 2414-3170/1/2/3/4/5
Fax:(+202) 2414-3179