Ursotwin is of great benefit regarding the Dose Flexibility and high Patient Comlpiance specifically in Advanced Liver Diseases mainly:
(1) Primary sclerosing cholangitis: Inflammation and fibrosis of intra &/or extra-hepatic bile duct system, with doses up to 30mg/kg/day.
(2) Primary Biliary Cirrhosis: Cholestatic disorder due to destruction of small and intermediate sized intrahepatic bile ducts.
(3) Intrahepatic Cholestasis in Pregnancy: Cholestasis of pregnancy associated with high fetal risk.It was difficult or nearly impossible to treat it in the past. It results in bile acids crossing the placenta.
(4) Non Alcoholic Steato-Hepatitis (NASH): To denote chronic liver disease associated with steatosis and inflammatory response with an increase in liver enzymatic activity, in absence of considerable alcohol consumption, viral or autoimmune hepatitis.