Hydroquine is antirheumatic drug used in cases of autoimmune diseases such as rheumatoid arthritis or systemic lupus, with economic price. Dose: 2 tabs/day initially followed by 1 tab/day as maintenance.
Rheumatoid arthritis is an auto immune disease, affecting the joints of the body, causing inflammation and deformation of the affected joints.
Arthritis may not only affect the joints, but may affect any organ of the body which is known as lupus erythmatos.
COMPOSITION:
Each film coated tablet contains 200mg Hydroxychloroquine sulphate.
INTERACTIONS:
Hydroxychloroquine increases plasma digoxin level and may also be subjected to several of Known interaction to chloroquine, these include: Potenitiation of its direct blocking action at the neuromuscular junction by aminoglycosides.Inhibtion of its metabolism by cimetidine resulting in increase of its plasma levels .By virtue of its immtmomodulatory action, it reduces the antibody response to primary immunization with intradermal human diploid cell. Rabies vaccine. The use of antacids reduces its absorption and four —hour interval spacing should be considered when antacid are used.
DOSAGE AND ADMINSTRATION:
Hydroquine Film Coated Tablets.pdf
Hydroquine can be given for jeuvenile arthritis starting from 2 years old.
2 tablets daily for 4-6 weeks, followed by 1 tab/day for maintenance.
Only minimal GIT disturbances.
Hydroquine can cause retinopathies, but unlikely to occur with the recommended dose. Fundus examination is recomended in long term therapies every 6 months. In rare cases of proven eye affection, the drug should be discontinued.