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Effox ® Biphasic 25, 50 mg Capsules

Isosorbide-5-mononitrate 50 mg for the management of coronary aretry disease. In biphasic release formulation, 30% immediate release & 70% sustained release to provide risk adjusted protection with once daily dosage and nitrate free interval.

Ingredient: Isosorbide-5-mononitrate Biphasic
Multinational Partner: Schwarz Pharma
Launch Date: May 1, 2002
Pack: Box of 20 capsules

Product General

Disease Area
  • Long-term treatment of coronary artery disease.
  • Long-treatment and prevention of angina pectoris (even after treated myocardial infarction).
  • Long-term treatment of chronic heart failure in combination with cardiac glycosides, diuretics, ACE-inhibitors or arterial vasodilators.
  • Pulmonary Hypertension.
Insert leaflet

Composition

Isosorbide 5-mononitrate 50 mg in biphasic release formulation, 30% immediate release & 70% sustained release for risk adjusted protection.

Indications

Long term treatment of coronary artery disease. Prophylaxis of anginal attacks; post-treatment of myocardial infarction with persisting anginal symptoms; long term treatment of chronic congestive heart failure in combination with digitalis and/or diuretics; chronic cor pulmonale.

Side Effects

Headache (less frequent than with others) & subsides gradually upon continuing treatment).

Dosage and Administration

One to two capsules once daily.

Packaging

20 capsules

Publications

1-Documents Section

Circadian variation of ishaemia in patients with coronary artery disease


ISMN Vs GTN


Nitrates for stable angina


Once daily therapy

Guidelines

In the Most recent Guidelines of the European Society of Cardiology (SCAD) for the management of Stable Coronary Aretry Disease (SCAD);

Nitrates were recommended for the relief of Angina/ Ischaemia.

Attached Files

Esc 2013-SCAD.PDF
Mechanism of action movie

1-Video Section

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Phone: (+202) 2414-3170/1/2/3/4/5
Fax: (+202) 2414-3179

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